CLINICAL SCIENCE Squamous cell carcinoma of the eyelids
نویسندگان
چکیده
Aim: To review the clinical features, management, and outcomes of surgical treatment of eyelid squamous cell carcinoma (SCC). Methods: A retrospective review of all eyelid SCCs treated between 1992 and 2001. Results: 51 cases were identified in 50 patients. Patient ages ranged from 26 to 93 years, with a mean age of 65 years. 33 patients were male and 17 were female. The lesion was found on the lower lid in 31 cases, upper lid in five cases, lateral canthus in six cases, and medial canthus in nine cases. Perineural invasion was found in four patients, and orbital invasion in three patients. Recurrence occurred in one patient. Treatment was by complete excision with histological confirmation of clear margins. Exenteration was required in three patients. No patients developed lymph node or distant metastases. One patient, who declined treatment, died as a result of the tumour. Mean follow up was 31.1 months. Conclusions: Eyelid SCC is a relatively uncommon, but potentially fatal disease. However, if detected early and treated adequately, the prognosis is generally excellent. Treatment by complete excision with histological confirmation of tumour clearance is recommended. Perineural spread is an adverse prognostic sign, which may require postoperative radiotherapy. Orbital invasion is a rare complication but, if recognised early, can be treated effectively with exenteration. Because presentation varies and histological examination is required for accurate diagnosis, any suspicious lesion occurring on the eyelids should be excised or biopsied. All patients with eyelid SCC should be advised of the risk of recurrent or new tumours and encouraged to attend lifelong follow up. Prevention remains of prime importance in minimising the morbidity and mortality of these lesions.
منابع مشابه
Primary Pure Squamous Cell Carcinoma of Gallbladder Presenting as Acute Cholecystitis
Squamous cell carcinoma of the gallbladder is rare and constitutes only 0.5-3% of all malignancies of this organ. Most of the reported cases have had a component of adenocarcinoma. We report a 70-year-old man who presented with acute onset right upper quadrant pain. He operated on based on a presumptive diagnosis of acute cholecystitis according to clinical and ultrasonographic findings. Histop...
متن کاملBasal cell carcinoma in patients referred to Imam Khomeini Hospital in Ahwaz in 1366-76
Background: Basal cell carcinoma (BCC) is the most common skin cancer in humans showing various clinical and histological forms. Objective: The aim of this study was to evaluate the age, sex, location, histological subtypes of BCC cases in Ahwaz and to compare it with other skin cancers specially squamous cell carcinoma. Patients and Methods: A descriptive, retrospective study was done using fi...
متن کاملPrognostic and Predictive Clinical, Pathological and Molecular Markers for Oral Squamous Cell Carcinoma: review of articles
Approximately 90% of all head and neck malignancies and 94% of oral malignancies are squamous cell carcinoma (SCC). Tobacco smoking is considered as the most important causative agent for SCC. Despite aggressive and multidisciplinary treatment approaches, there has been no significant improvement in 5-year survival over the past 20 years. Several prognostic and predictive clinical, pathological...
متن کاملCytodiagnosis of Cutaneous Basal and Squamous Cell Carcinoma
Background and Objective: Cutaneous cytology is the study of scraping or smears obtained from skin lesions. Although not commonly employed, cutaneous cytology has been a useful tool for clinicians due to simplified procedures and high sensitivity and specificity of presurgical clinical diagnosis of commo...
متن کاملShort communication: Occurrence of squamous cell carcinoma in a platy fish (Xiphophorus maculatus): A case report
متن کامل
Matrix Metalloproteinase Expression Significance on Oral squamous cell carcinoma Clinical Outcome
Introduction:Oral Squamous Cell Carcinoma (OSCC) is an invasive neoplasm with a high prevalence. Matrix Metalloproteinase (MMP) has been thought to play an important role in both the invasion and metastasis of tumors. The aim of this study was to explore the significance of MMPs expression in clinical outcome of these patients. Materials:The most recognized data Bases such as PubMed, Google sc...
متن کامل